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I'm so glad I found this Collagen Boosting Cream! It's the perfect way to nourish and protect my skin overnight. After just a few uses, I noticed softer, more supple skin in the morning — it's amazing!
Clara E.
This is definitely one of the best skincare products I've used. The cream deeply hydrates and repairs skin overnight, leaving me with firmer, plumper skin by morning! Plus, it doesn't contain any harsh chemicals like parabens or fragrances.
Chris

Collagen Boosting Cream

36 reviews 36 total reviews

Dual-Peptide Expression Line Cream

Regular price
$69.00
Regular price
$0.00
Sale price
$69.00
Shipping calculated at checkout.

Expression lines persist after the face relaxes because the structural scaffold beneath them — collagen and elastin — has thinned. This cream works at that structural layer, not the surface.

  • Syn®Coll peptide signals fibroblasts to increase collagen output, improving firmness over weeks
  • Acetyl Hexapeptide-8 reduces neurotransmitter release at muscle junctions, softening repeated-contraction lines
  • Proline and Lysine deliver the molecular building blocks collagen synthesis requires directly to the dermis

For skin 45+ where structural decline has outpaced surface repair.

TRY IT FOR 60 DAYS FIRST

SMALL BATCH PRODUCTIONS

SAME DAY SHIPPING

Skin Profile

After 40, two distinct processes converge: collagen production slows, and years of repeated muscle contractions have permanently scored expression lines into skin. Standard moisturisers address neither. This cream deploys Syn®Coll to reactivate fibroblast-level collagen synthesis, Amino Acids Proline and Lysine as direct molecular feedstock for that synthesis, and Copper as a cofactor for both collagen and elastin. Hyaluronic Acid supports barrier hydration throughout. Used nightly, it progressively rebuilds structural firmness from within.

How to use
  1. Apply nightly to clean, dry face and neck after any serum step.
  2. Use a pea-sized amount — warm between fingertips before pressing gently into skin rather than rubbing.
  3. Focus on the forehead, eye area, and jaw where expression lines and firmness loss are most active.
  4. Allow 60–90 seconds to absorb before lying down. No additional moisturiser needed on top.
  5. Use consistently for a minimum of 28 days to complete one full cell turnover cycle.
Key Ingredients

Syn®Coll (Palmitoyl Tripeptide-5) — Patented peptide that directly activates fibroblast signalling pathways to stimulate Type I collagen synthesis. Improves skin elasticity with measurable results over weeks.

Acetyl Hexapeptide-8 (Argireline) — Inhibits SNARE protein complex activity, reducing the neuromuscular contractions responsible for expression line formation. Topical, non-injection alternative with documented efficacy.

Hyaluronic Acid — Binds up to 1,000× its weight in water at the dermal level. Supports structural hydration rather than surface-only moisture retention.

Amino Acids (Proline & Lysine) — Direct molecular precursors to collagen. Without adequate Proline and Lysine, the body cannot assemble new collagen triple-helix structures regardless of fibroblast activity.

Copper — Activates lysyl oxidase, the enzyme that cross-links collagen and elastin fibres. Also functions as a cofactor in superoxide dismutase antioxidant defence.

Porphyra umbilicalis (Nori-Red Algae) Extract — Contains porphyran and mycosporine-like amino acids, which absorb UV-range radiation and reduce photo-oxidative stress at the skin surface.

Green Tea Extract — Delivers EGCG (epigallocatechin gallate), which inhibits inflammatory cytokine pathways. Reduces irritation response, supporting tolerance in sensitised skin.

+ See Full Ingredients

I'm so glad I found this Collagen Boosting Cream! It's the perfect way to nourish and protect my skin overnight. After just a few uses, I noticed softer, more supple skin in the morning — it's amazing!
Clara E.
This is definitely one of the best skincare products I've used. The cream deeply hydrates and repairs skin overnight, leaving me with firmer, plumper skin by morning! Plus, it doesn't contain any harsh chemicals like parabens or fragrances.
Chris
A jar of ONSEN Secret Collagen Boosting Cream with a clear blue label, indicating it&
A jar of ONSEN Secret Collagen Boosting Cream with a clear blue label, indicating it&
collagen boosting cream
Japanese Healing Traditions
Awakens Self Healing
It's safe
It's One Of A Kind

Why You’ll Love It

collagen boosting cream

Why You’ll Love It

Fibroblast Type I collagen output signalled nightly
Acetyl Hexapeptide-8 reduces SNARE-driven muscle contraction
Proline and Lysine feed new collagen synthesis directly
Hyaluronic Acid binds moisture at the dermal level
Copper activates lysyl oxidase for elastin cross-linking
Expression line depth visibly reduced over 4 weeks

The Muscle Movement Behind Every Expression Line

In 2001, researchers at Lipotec in Barcelona set out to find a topical alternative to neurotoxin-based injections for expression lines. The result was Acetyl Hexapeptide-8 — a peptide that reduces the release of neurotransmitters at facial muscle junctions, limiting the repeated micro-contractions that etch lines into the skin over years. The molecule is small enough to reach the neuro-muscular junction transdermally, something collagen molecules cannot do. Two decades of independent study have since validated its mechanism in peer-reviewed literature. Onsen incorporates it alongside Syn®Coll for a dual-pathway approach: structural rebuild and muscular softening simultaneously.

Your questions, answered.

Can I use this alongside a retinoid or vitamin C serum?

Yes. Apply the retinoid or vitamin C first, allow it to absorb fully, then layer this cream on top. The peptides in this formula are stable and do not deactivate in the presence of retinoids. Avoid mixing directly with high-strength acids, which can disrupt peptide bonds.

How long before I see a measurable difference in firmness?

Cell turnover takes approximately 28 days. Most users report a change in skin texture and density by week four of nightly use. Collagen reorganisation is a slower process — structural changes in firmness typically become visible between weeks six and eight with consistent application.

Is this suitable for skin that reacts easily to fragrance or synthetic additives?

The formula contains no synthetic fragrances, parabens, glycols, or colouring agents. Green Tea Extract and Nori-Red Algae both carry documented anti-inflammatory profiles. If your skin is reactive, patch-test on the jaw for three consecutive nights before full-face application.

Does this cream help with dark spots or uneven skin tone?

Yes, the Vitamin C and Onsen minerals help brighten and even out skin tone, improving the overall radiance and clarity of your complexion.

Is there a risk-free trial?

Absolutely! We want you to feel completely confident in your purchase. That’s why the Dual-Peptide Expression Line Cream comes with a 60-day money-back guarantee. Try it, love it, and if it’s not everything you hoped for, we’ll happily refund your purchase—no questions asked. Your happiness is our priority!

Why Putting Collagen On Your Skin Doesn't Work

Collagen is a large molecule. Applied to skin, it cannot cross the dermal barrier — it conditions the surface at best. Meanwhile, your skin's own production drops roughly 1% per year after 30, and nothing on the surface reverses that. Syn®Coll (Palmitoyl Tripeptide-5) changes this by mimicking the signal that activates fibroblasts — the cells that actually manufacture collagen. No collagen is introduced from outside. The skin's own synthesis mechanism is switched back on. That is a structural fix, not a cosmetic one.

Why Choose Our Products

Elevate Your Skincare Routine with Our Superior Products

Our Products

Suitable for All Skin Types
Formulated to be safe and effective for even the most sensitive skin

Gentle & Non-Damaging
Renews and regenerates skin cells without irritation or damage

Comprehensive Skincare
Covers all your skincare needs for a complete daily regimen

Customize Skin Solutions
Tailored to address multiple specific skin concerns and types

Glowing, Healthy Complexion
Healthy-looking complexion that boosts your confidence

Others

Harsh Formulations
Use of strong chemicals that can cause irritation and damage skin

Inconsistent Short-Term Results
Results vary, making it difficult to achieve consistent skin improvements

Artificial & Filler Ingredients
Contain synthetic and unnecessary ingredients that offer little benefit

Limited Skincare Range
Fails to address multiple skincare needs at the same time

Inadequate Hydration
Leaves skin feeling dry and tight instead of rejuvenated

  • 5 stars: 31 (86%)
  • 4 stars: 4 (11%)
  • 3 stars: 1 (3%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
V
Viola McGregor (Newark, US)
Changes

I still have this product in the jar. Not fond of new packaging in the tube. Feel one never gets all out. Also very tiny compared to the jar.
The cream in the past has been great. Hope the formula is the same.

A
Alicia Guastaferro (Buffalo, US)
Love it!

Leaves my skin feeling refreshed I put it on every night!

L
Leona C.
Say Goodbye to Dry Skin!

Dry skin no more! Thanks to this wonderful Collagen Boosting Cream, my skin now feels adequately nourished throughout the night. The formula is lightweight, nongreasy, and easily absorbed. I'm happy with the added bonus of Green Tea Extract for a soothing touch, making it perfect for bedtime.

A
Alma S.
Radiance in a Jar!

Onsen Secret's Sleep Therapy Moisturizer has brought radiance back to my skin. I've been using it consistently, and the results are fantastic. My complexion looks healthier, and the fine lines have reduced. It's a delight to apply before bed, knowing it's free from harsh chemicals that could harm my skin.

P
Pearl S.
Beauty Sleep in a Bottle!

This moisturizer is like beauty sleep in a bottle! I'm in love with how it deeply nourishes and rejuvenates my skin overnight. The collagenboosting properties are impressive, and the absence of harsh chemicals makes it a winner for me. My skin looks forward to bedtime now!

E
Earlene L.
Youthful Glow Unlocked!

Unlock your youthful glow with this Collagen Boosting Cream! The effects on my skin have been remarkable. It feels more supple, and the increased elasticity is noticeable. I adore that it's packed with natural goodness and free from any harmful substances. I'm excited to see the longterm benefits.

A
Antoinette W.
Beauty Sleep Essential!

This Collagen Boosting Cream has become a musthave in my nighttime ritual. Not only does it smell wonderful, but it also deeply nourishes my skin. My complexion feels firmer, and I've noticed a visible improvement in skin elasticity. Plus, knowing that it's free from harmful chemicals makes me feel confident about using it regularly.

C
Colette C.
A Dream for My Skin!

I've found my dream moisturizer with Onsen Secret Sleep Therapy! It absorbs quickly into my skin, leaving it feeling hydrated and revitalized. The collagenstimulating properties have made my skin feel plumper and more youthful. I appreciate the absence of harsh chemicals, making it gentle on my sensitive skin.

B
Blanche M.
Nighttime Magic!

The magic happens overnight with this Collagen Boosting Cream. I was amazed by how much smoother and refreshed my skin looked in the morning. The soothing power of Green Tea Extract is evident, and I love that it's allnatural without any questionable ingredients. My skin thanks me every morning!

K
Kristie H.
Wake Up to Radiant Skin!

The Onsen Secret Sleep Therapy Moisturizer truly lives up to its promise! After incorporating it into my bedtime routine, I woke up with noticeably softer and more supple skin. The collagenboosting formula works wonders, and I love that it contains Green Tea Extract for soothing without any harsh chemicals. Highly recommended!

E
Elena M.
Beauty Rest, Realized!

Finally, a product that truly gives me beauty rest! Onsen Secret's Sleep Therapy Moisturizer has been a gamechanger for my skincare routine. My skin feels firmer, and the overall texture has improved significantly. I'm also delighted that it's free from parabens, fragrances, and harmful chemicals. A definite win!

F
Fanny E.
Soothing Skincare Perfection!

Onsen Secret's Sleep Therapy Moisturizer is skincare perfection! The soothing Green Tea Extract complements the hydrating formula beautifully. I've noticed a significant improvement in my skin's firmness and elasticity. It's a wonderful addition to my nighttime routine and a fantastic way to wake up to a radiant complexion!

L
Lynn S.

This collagen cream does more than you can imagine. It has completely refined the cellulite on my upper arms that I thought would require surgery. If I was more regular with arm workouts I know my arms would look twenty years younger, but in the meantime this collagen booster is working wonders! I’m on my 5 th jar!

This is much appreciated, Lynn. Super thrilled that you are happy and satisfied with your purchase. We put customer experience and satisfaction as our priority, and your review reaffirms the hard work we put in every day. I'm sure you will also LOVE our other skincare and nail products. Thank you so much for being one of our loyal customers. ❤️

S
Susan G.

replenishes fullness of skin

Thanks, Susan!

L
Lynn S.

INCREDIBLE DIFFERENCE in crepey arm skin and even cellulite in upper arms over 3 weeks. Unbelievable. Amazing!

Wow, Lynn!! Thank you so much for sharing your review. We are so happy that our product makes a difference in just 3 weeks. We're excited for you to try our other products.

S
Sylvia Robinson (Ashburn, US)
Collagen Boosting Cream!

This product is fantastic. I noticed my skin was
hydrated, smoother, and plumper after using the cream for Seven days. Thank you, Onsen!

S
Sylvia R.

After two days, I noticed a reduction in the wrinkles across my forehead, and my face felt more plumped.

Woohoo! Thanks so much for your 5-star review on our Collagen Boosting Cream. We appreciate you taking the time to post a review.

N
Nancy Frank (Asheville, US)
A great investment in self care!

The light affect and deep and expansive coverage of the cream is wonderful!

P
Pam Briggs (Portland, US)
Very nice product

I use it at night as a last step after I cleanse with the Aloe Cleansing lotion, followed by the Clean & Clear Toner … My skin immediately feels plumper and smooth. I have been a long-time fan of the entire Onsen Secret facial and nail care products, and this one is no exception. Only wish management would come up with more sustainable packaging. I understand the benefits of plastic packaging, but I feel we have to actively pursue alternatives in order to save our planet from the disastrous effects of climate change.

P
Pam Briggs

Very nice product
I use it at night as a last step after I cleanse with the Aloe Cleansing lotion, followed by the Clean & Clear Toner … My skin immediately feels plumper and smooth. I have been a long-time fan of the entire Onsen Secret facial and nail care products, and this one is no exception. Only wish management would come up with more sustainable packaging. I understand the benefits of plastic packaging, but I feel we have to actively pursue alternatives in order to save our planet from the disastrous effects of climate change.

D
Debra Ruf carson (Holliston, US)
Excellent product!

Smoothing and brightening effects from a light pleasant cream.

Thank you
Debra

D
Debra Ruf carson

Excellent product!
Smoothing and brightening effects from a light pleasant cream.

Thank you
Debra

D
Donna Froncillo (Incline Village, US)
It works!

I love the products and will be buying more in the future. I wish for more sales so I can buy the whole line. 😊 Collagen is the most important as we age. Your formula is amazing. Makes my skin soft. My favorite is the eye cream dark circles.

D
Donna Froncillo

It works!
I love the products and will be buying more in the future. I wish for more sales so I can buy the whole line. 😊 Collagen is the most important as we age. Your formula is amazing. Makes my skin soft. My favorite is the eye cream dark circles.

E
Ella Litvak (Boston, US)

Collagen Boosting Cream

E
Ella Litvak

Collagen Boosting Cream

S
Sheryle Hill (Portland, US)

Love this product my shin is softer and younger looking

S
Sheryle Hill

Love this product my shin is softer and younger looking

A
Anna Hollingworth (Twickenham, GB)
Collagen Boosting Cream

I love this cream. My skin is fresher and visibly happier. I had compliments from my friends who wanted to know what cream I am using.

C
Customer

Collagen Boosting Cream
I love this cream. My skin is fresher and visibly happier. I had compliments from my friends who wanted to know what cream I am using.

C
Cheryl Fitch (Phoenix, US)
Great results for older skin

I used this product many years ago and didn't really notice anything. Now I am in my early 60s and WOW! This product truly does make a difference! My skin is more hydrated, plumper, and more youthful looking. I also use the under eye serum and the collagen boosting serum. LOVE the results!