• A bottle of Onsen Time-Freeze Tenseless Serum with blue and white labeling, designed for skincare.
  • Anti-Aging & Firming Serum
  • anti wrinkle serum for sensitive skin
1 3
Amazing. I can already see the difference in my skin. The serum is fast-absorbing and doesn't leave any oily residue. It has reduced the appearance of wrinkles and fine lines, and my skin feels firmer and more elastic. I also appreciate that it protects my skin against free radicals and supports my facial muscles. I definitely recommend this serum to anyone looking for an effective anti-aging solution.
Matt D.
I am always on the lookout for a great anti-aging serum, and Onsen Secrets Time-Freeze Tenseless Serum is definitely one of the best I have tried. The serum is super-concentrated and enriched with powerful anti-aging ingredients like Apple Stem Cells and Peptides. It has improved the overall texture and tone of my skin, making it smoother and more radiant
liz H.

Time-Freeze Tenseless Serum

24 reviews

SYN-AKE Muscle-Relaxing Serum

$169.00
$0.00
$169.00
Shipping calculated at checkout.

Expression lines form over 15,000 daily muscle contractions. This serum targets the subcutaneous muscle layer — not the surface — to interrupt that cycle from within.

  • SYN®-AKE relaxes facial muscle fibres for up to 8 hours per application
  • Swiss Apple Stem Cells activate skin's own regenerative stem cells
  • Neodermyl® and Syn®Coll signal collagen synthesis via two distinct peptide pathways

For adults over 45 with visible expression lines and measurable elasticity loss.

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Skin Profile

Expression lines form from two compounding problems: subcutaneous muscle tension that carves lines deeper with each contraction, and a dermis too depleted to recover. SYN®-AKE relaxes facial muscle fibres for up to 8 hours per application. Neodermyl® and Palmitoyl Tripeptide-5 stimulate collagen synthesis through complementary peptide pathways. Swiss Apple Stem Cells reactivate the skin's own regeneration cycle. Hyaluronic Acid maintains barrier hydration throughout. Consistent use over 4–6 weeks reduces contraction depth and rebuilds structural resilience.
How to use
  1. Apply to clean, dry face and neck morning and evening.
  2. Dispense 3–4 drops and press gently into skin — focus on forehead, between brows, and crow's feet where muscle tension concentrates.
  3. Allow 60 seconds to fully absorb before layering moisturiser or SPF.
  4. For best results, use consistently for a minimum of 8 weeks — collagen and stem cell changes accumulate over time, not overnight.
Key Ingredients

SYN®-AKE (Dipeptide Diaminobutyroyl Benzylamide Diacetate) — Patented peptide that reduces subcutaneous facial muscle contractions for up to 8 hours, directly targeting expression line formation at the source.

Neodermyl® — Patented copper peptide that activates fibroblast activity in the dermis, stimulating collagen production and measurably improving skin elasticity over time.

Syn®Coll (Palmitoyl Tripeptide-5) — Patented peptide that signals collagen synthesis through a distinct pathway, complementing Neodermyl® to rebuild structural skin density.

Swiss Apple Stem Cells — Extracted from a rare long-lived Swiss cultivar; reactivates dormant skin stem cells to support cellular regeneration beyond the epidermis.

Vitamin C — Antioxidant that neutralises free radical damage, protecting collagen already present while supporting an even skin tone over continued use.

Resveratrol — Polyphenol antioxidant that defends against oxidative stress and supports the skin's structural elasticity alongside the collagen-stimulating peptide complex.

Hyaluronic Acid — Draws and binds moisture within the skin matrix, maintaining the hydration environment the peptide and stem cell actives need to function effectively.

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Full Ingredients List

Onsen Hot Springs Minerals Distillate™ (Aqua, Calcium, Tourmaline, Thujopsis Dolabrata Branch Extract), Dipeptide Diaminobutyroyl Benzylamide Diacetate (SYN®-AKE), Palmitoyl Tripeptide-5 (Syn®Coll), Simmondsia Chinensis (Jojoba) Seed Oil, Cetyl Alcohol, Ceteareth-20, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Vitis Vinifera (Red Wine) Resveratrol Extract, Sodium Ascorbyl Phosphate (Vitamin C), Phenyltrimethicone, Dimethicone, Acetyl Hexapeptide-8, Cyclomethicone, Porphyra umbilicalis (Nori-Red Algae) Extract, Malus Domestica Fruit Cell Culture Extract, Trimethylsiloxysilicate, Hyaluronic Acid, Methyl Glucoside Phosphate Proline Lysine Copper Complex (Neodermyl®), Aloe Barbadensis (Organic Aloe Vera) Leaf Juice, Camellia Sinensis Leaf (Organic Japanese Green Tea) Extract, Phenoxyethanol, Disodium Acetyl Glucosamine Phosphate (NovHyal®), Euterpe Oleracea Mart (Organic Acai) Extract, Xanthan Gum, Tocopheryl Acetate (Vitamin E), Retinyl Palmitate (Vitamin A), Lavandula Angustifolia (Lavender) Oil, Ethylhexylglycerin.

Amazing. I can already see the difference in my skin. The serum is fast-absorbing and doesn't leave any oily residue. It has reduced the appearance of wrinkles and fine lines, and my skin feels firmer and more elastic. I also appreciate that it protects my skin against free radicals and supports my facial muscles. I definitely recommend this serum to anyone looking for an effective anti-aging solution.
Matt D.
I am always on the lookout for a great anti-aging serum, and Onsen Secrets Time-Freeze Tenseless Serum is definitely one of the best I have tried. The serum is super-concentrated and enriched with powerful anti-aging ingredients like Apple Stem Cells and Peptides. It has improved the overall texture and tone of my skin, making it smoother and more radiant
liz H.
A bottle of Onsen Time-Freeze Tenseless Serum with blue and white labeling, designed for skincare.
Anti-Aging & Firming Serum
anti wrinkle serum for sensitive skin
Japanese Healing Traditions
Awakens Self Healing
It's safe
It's One Of A Kind

Why You’ll Love It

Anti-Aging & Firming Serum

Why You’ll Love It

8-hour subcutaneous muscle relaxation
Expression lines softened from week one
Two patented peptides rebuild dermal collagen
Forehead and crow's feet lines reduced
Stem cell regeneration cycle activated
Lightweight finish — no residue or occlusion

The Swiss Apple with a 200-Year Lifespan

Most apple varieties have a shelf life measured in weeks. One rare Swiss cultivar — Uttwiler Spätlauber — stores for months. The reason: unusually long-lived stem cells that continue repairing the fruit long after harvest. Researchers extracted those stem cells and found they could activate human skin stem cell renewal — not a surface effect, but a signal to dormant regenerative cells within the skin itself. As skin ages past 40, its own stem cell activity slows. Swiss Apple Stem Cells give it a reason to restart.

Your questions, answered.

How is this different from a standard peptide serum?

Most peptide serums work at the surface — hydrating or temporarily plumping. This serum includes SYN®-AKE, a peptide that acts on the subcutaneous muscle layer to reduce the contractions that cause expression lines. That's a different mechanism from surface hydration entirely.

How quickly will I see results?

Muscle relaxation from SYN®-AKE is detectable within hours of application. Structural changes — collagen density, elasticity, visible line depth — build over 4–8 weeks of consistent use. The serum works on two timelines simultaneously.

Can I use this alongside other actives in my routine?

Yes. Apply this serum to clean skin before moisturiser. It layers compatibly with SPF in the morning. Avoid applying directly on top of strong exfoliating acids in the same step — use those on alternate evenings if needed.

How often should I use the Time-Freeze Tenseless Serum for the best results?

For optimal results, use daily, preferably in the morning and night, after cleansing. For best results, pair it with other skincare treatments in your routine.

Is there a risk-free trial?

Absolutely! We want you to feel completely confident in your purchase. That’s why the SYN-AKE Muscle-Relaxing Serum comes with a 60-day money-back guarantee. Try it, love it, and if it’s not everything you hoped for, we’ll happily refund your purchase—no questions asked. Your happiness is our priority!

Why Serums Don't Fix Lines Made by Muscle

Botox reduces wrinkles by blocking nerve signals to facial muscles. It works because it acts at the right layer — subcutaneous, not epidermal. Most topical serums never reach that layer. They deposit actives on or just below the skin's surface, where no muscle fibre exists to be influenced. SYN®-AKE is a synthetic peptide engineered to mimic the neuromuscular-blocking protein found in temple viper venom. Carried by Onsen Water's micro-cluster structure into deeper tissue, it reduces muscle contraction at the source — the mechanism botox uses, without the needle.

Why Choose Our Products

Elevate Your Skincare Routine with Our Superior Products

Our Products

Suitable for All Skin Types
Formulated to be safe and effective for even the most sensitive skin

Gentle & Non-Damaging
Renews and regenerates skin cells without irritation or damage

Comprehensive Skincare
Covers all your skincare needs for a complete daily regimen

Customize Skin Solutions
Tailored to address multiple specific skin concerns and types

Glowing, Healthy Complexion
Healthy-looking complexion that boosts your confidence

Others

Harsh Formulations
Use of strong chemicals that can cause irritation and damage skin

Inconsistent Short-Term Results
Results vary, making it difficult to achieve consistent skin improvements

Artificial & Filler Ingredients
Contain synthetic and unnecessary ingredients that offer little benefit

Limited Skincare Range
Fails to address multiple skincare needs at the same time

Inadequate Hydration
Leaves skin feeling dry and tight instead of rejuvenated